Principle
Kligman’s trio is a magistral preparation using hydroquinone, that is prescribed by a dermatologist and prepared by a pharmacist. This skincare product is one of the most effective at fighting spots on the skin and hands. Because Kligman’s trio is unstable and oxidizes quickly when exposed to light, the preparation should be refrigerated and replaced monthly. Medical follow-up is imperative throughout use of the product.
Results
The depigmenting effects can be seen beginning in the second week. A maintenance product is necessary because the effect is only temporary.
Possible side effects
The side effects of hydroquinone may include irritation or contact allergy. White spots have even been described after prolonged usage at strong concentrations in patients with high phototypes.